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Hugo Kubinyi Phosphodiesterases and Their Inhibitors


Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases. Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.

15961.07 RUR

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The Big Book of Sex Quotes : 1001 Quips and


Book Description"When authorities remind you of the sinfulness of sex, there is an important lesson to be learned. Do not have sex with the authorities."--Matt Groening (The Simpsons). Prudes beware: there are no repressive authoritiesor censors here. From Aphrodisiacs to Rude Food, Virginity to Viagra, these 1001 unexpurgated sex quotes--divided into 75 categories--are too good to keep under cover. As with every volume in the popular "Big Book" series, the seductive array of materialcovers a wide span, and nothing is too hot to handle. Some are fresh off the press: "Study Finds Sex-Pregnancy Link" trumpets one newspaper headline. (Who knew?) Others come from our finest comic geniuses, such as Woody Allen's "Sex without love is anempty experience, but as empty experiences go, it's one of the best." Whether it's Mae West's sassy "To err is human--but it feels divine" or Andy Warhol's surprising "Sex is the biggest nothing of all time," these are entertaining and amazing.

167 RUR

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